Using GENOME with a Stereo Amp DI

Using GENOME with a Stereo Amp DI

In the following knowledgebase article we highlight how to configure GENOME - or multiple instances of GENOME - to work alongside a Stereo DI signal, be it a Pedalboard, Physical Amp / Loadbox or Modelling Processor.

What is a Stereo DI?

A Stereo DI is essentially two channels of audio, hard panned with one channel outputted via the Left Speaker channel and the other outputted via the Right Speaker channel.

Does GENOME Accept a Stereo Signal?

Yes, with the update 1.03, GENOME has been configured to process a stereo or a mono signal at its input stage and there are dedicated options to select how a Stereo Signal is processed into a compatible Mono source. These are:

  • Stereo: In this instance, the stereo signal at the input is processed in stereo by GENOME
  • Mono LR Mix: In this instance both channels of the Stereo signal are summed to a Mono signal
  • Mono from Left: In this instance GENOME takes the left channel of the Stereo signal only
  • Mono from Right: In this instance GENOME takes the right channel of the Stereo signal only
For Genome V1.02:  GENOME only works with a Mono Signal Source. Within GENOME’s lane-based architecture and component arsenal, Mono to Stereo signal conversion is automatically administered in order to keep you focussed on creating exceptional guitar tones. With a Stereo signal input, GENOME’s component arsenal and lane based architecture could compromise your signal resulting in some unfavourable results when it comes to configuring your signal path.

Having issues?
Our support team is here to assist you! For any enquiries, please head over to our Help Desk and submit a ticket to speak directly to one of our in-house specialists.




    Limited Service Notice
    Please be advised, we are currently running a limited Help Desk Service from the 06th to the 12th of June 2025.

    Rest assured, your enquiry is of the utmost importance to Two notes Audio Engineering and our support team are committed to resolving your enquiry as a matter of priority upon their return.

    If you have licence issues with our software, close the software then go to this page  https://www.two-notes.com/en/my-two-notes/?section=software

    Click on the RENEW button to renew your licence, and open the software again.





      • Related Articles

      • How does GENOME handle mono & stereo signals

        In the following knowledge-base article we highlight how GENOME is configured for Mono and Stereo Signal processing both at the input stage and within the component level processing of the application. GENOME's Input Stage GENOME (V1.03) has been ...

      • Audio Routing Troubleshooting

        In this article, we run through common troubleshooting steps for users experiencing audio routing issues, often resulting in no sound when using GENOME both live with your instrument and/or playing-back recorded audio. When Playing GENOME Live With ...

      • Amplifier & Effect Routing With a Torpedo Loadbox

        The location of your effects (pedals or multi-FX) within your signal chain is very important. You can of course follow the usual rules concerning effects layout, with certain effects placed before a preamp (OD, fuzz, compressor etc.), or in the ...

      • OPUS's AUX Input & Phones Output - Stereo & Mono Signals

        When using the AUX input and the headphone output, the user case scenarios in regards to mono and stereo signals are outlined below: The AUX IN accepts stereo signals at its input. The signal will be played in stereo via the headphone output. The AUX ...

      • Best Practice When Using GENOME's Component Arsenal

        In the following support article we take a look at some top tips when structuring your RIG using GENOME’s ever expanding suite of TSM Amplifiers, CODEX Captures, DynIR Engine / IR Loader and PEDALS. NOISE GATE GENOME’s Noise Gate is positioned at the ...