How to Use GENOME with OPUS

How to Use GENOME with OPUS

GENOME has been specified to work seamlessly alongside our digital amp simulator and DynIR Engine, OPUS.

Considerations for all OPUS Setup Scenarios

As GENOME is a plugin application, you will need to have the following studio peripherals available to integrate OPUS into a GENOME-centric workflow:
  1. An audio interface with suitable line level inputs
  2. A Digital Audio Workstation (DAW) in which GENOME can be instantiated
  3. Suitable cabling to connect OPUS to your audio interface
For real-time playback, configuring your audio settings within your DAW is paramount:
  1. Make sure you are using the latest drivers for your audio interface for Windows; if your audio interface does not have dedicated drivers, use a third-party ASIO4ALL driver
  2. Set your buffer size and latency to as low as possible; when using GENOME if you experience pops and clicks while playing, you will need to raise this buffer / latency setting until these non-desirable artefacts are no longer audible. For guides on setting your audio preferences in all mainstream DAWs, please refer to the following articles:
    1. "Logic Pro"
    2. "Ableton Live"
    3. "Pro Tools"
    4. "Cubase"
    5. "Studio One"
    6. "GarageBand"
  3. Finally, if your interface features a zero-latency monitoring/direct monitoring option, please ensure this is disabled to avoid hearing your GENOME-processed and DI signal simultaneously

Technical Setup 

  1. Connect OPUS’ ¼-inch Line or XLR output to your audio interface
  2. Create an audio track in your DAW and configure its input and output routing in accordance with the input and output specifications of your interface
  3. Load GENOME on the audio track to apply the plugin's effects to your recorded or realtime signal

Using GENOME in a Setup Where OPUS is Connected Between Your Amp Head & Cabinet / Load box

In this setup, OPUS sends the full amp signal to GENOME. For best tonal results, do not use the following Components in GENOME:
  1. TSM Amplifiers or CODEX
  2. Drive PEDALS
  3. The DynIR Engine or IR Loader (this processing is already provided by OPUS
In OPUS' architecture, ensure the following processing blocks are disabled:
  1. TSM Preamp Emulation
  2. TSM Poweramp Emulation
You can then use GENOME’s suite of Post FX to build on your tone. Alternatively, disengage the DynIR engine and Post FX in OPUS and use GENOME’s dual lane routing options to create stereo cab and Post FX rigs.

Using GENOME where OPUS is Used on its Own or With Other Pedals

In this setup scenario, OPUS is providing the foundation tone via the built-in TSM preamp and poweramp emulations plus the DynIR Engine; in addition, you may be using additional pedals (or your full pedalboard) before OPUS. For best tonal results, do not use the following Components in GENOME:
  1. TSM Amplifiers or CODEX
  2. Drive PEDALS
  3. The DynIR Engine or IR Loader (this processing is already provided by OPUS
You can then use GENOME’s suite of Post FX to build on your tone. Alternatively, disengage the DynIR engine and Post FX in OPUS and use GENOME’s dual lane routing options to create stereo cab and Post FX rigs.

Advanced Setup Using OPUS's Dual Mono LINE OUT Routing

When tracking, using your interface’s zero latency monitoring mode is a great way of negating any buffer/latency issues within your DAW. Within OPUS’ menu, the LINE OUT ROUTING modes allow you to send a dry DI signal from the LINE ¼-inch output in tandem with a fully-processed signal from the XLR output.
  1. First, from the Preset Window on OPUS’ OLED display, push the right encoder to enter the Main Menu
  2. Then, navigate to the “Global” Menu (indicated by a cog icon) using the right encoder and push the right encoder to enter this menu
  3. Once inside the Global Menu, scroll to “LINE OUT ROUTING” using the right encoder
  4. Select the "NO PROCESSING" in the menu.
You’re set to track/record 2 different signals: the processed DI feed and the dry instrument DI which can be used in tandem with GENOME at the all-important mix-down stage.

Having issues?
Our support team is here to assist you! For any enquiries, please head over to our Help Desk and submit a ticket to speak directly to one of our in-house specialists.





    Limited Service Notice
    Please be advised that the Two notes Helpdesk will be running with a skeleton crew from this Friday 12th of April 2024 to Monday 15th of April (included). Our response time over this period will be slower than usual.
    Rest assured, your enquiry is of the utmost importance to Two notes Audio Engineering and our support team are committed to resolving your enquiry as a matter of priority upon their return to full staff.




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